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Tamoxifen and Endogenous Testosterone Levels

And now we will return to the question of the influence of two heroes of our today’s article on the restoration of the level of endogenous testosterone. Back in the distant 70s of the last century, one interesting study was carried out, which somehow everyone chose to forget about later. It was about comparing the effects of Clomid 100mg and tamoxifen on testosterone levels in people with normal hormonal levels and those suffering from oligospermia. We will be interested only in the results concerning “normal” people.

So, it turned out that the use of 20 mg of tamoxifen per day for the entire 10 days led to an increase in the level of endogenous testosterone by 42%. The same result was achieved when using 150 mg of clomid daily for the same period of time. It is not strange – as we remember, tamoxifen will be stronger than Clomid.

Three more benefits of tamoxifen and one drawback

Tamoxifen has three more advantages that make its use a priority over Clomid. First, this drug increases the level of high-density cholesterol (VHD) in the blood. It would be useful to remind you that exceeding the level of TOVP (“good” cholesterol) above the level of low density cholesterol (“bad”) reduces, and significantly, the risk of cardiovascular diseases, so characteristic of athletes at a competitive level.

Secondly, tamoxifen, by its very nature a very mild estrogen, exhibits estrogenic activity in the liver very clearly. Such its effect on the liver as a whole affects the body very positively (except for one case, which will be discussed below).

Third, tamoxifen is safer than Clomid 100mg. It has been established that the long-term use of clomid may have an irreversible effect on vision. Not in the direction of improving it, naturally. Of course, this effect is manifested only with long-term use of Clomid, and then not at all, but …

Well, now about the “fly in the ointment”, however, you have probably already guessed what it is about. Tamoxifen, although not to a very significant extent, still inhibits the production of insulin-like growth factor (IGF-1) by the body, this drawback arises from the advantage considered by the second. Clomid 100 mg, while less active in the liver as an estrogen, also has this disadvantage, but to a much lesser extent.